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Abstract
Polyethylene glycol (PEG) functionalized graphene quantum dots (GQDs-PEG) with average particle size of 2.1 nm were successfully prepared by hydrothermal method with PEG as surface passivation agent. The quantum yield (QY) of GQDs-PEG was 3.7%and its physiological stability was significantly better than that of GQDs. The cell viability assay results showed that GQDs-PEG display no obvious toxicity to cells. The results of cell fluorescence imaging showed that GQDs-PEG could enter the whole cell with high fluorescence recognition.
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Funding
This study was funded by the National Natural Science Foundation of China (21675091, 21574072, 21874078), the Taishan Young Scholar Program of Shandong Province (tsqn20161027), the Major Science and Technology Innovation Project of Shandong Province (2018CXGC1407), the Key Research and Development Project of Shandong Province (2016GGX102028, 2016GGX102039, 2017GGX20111), the Project of Shandong Province Higher Educational Science and Technology Program (J15LC20), the People's Livelihood Science and Technology Project of Qingdao (166257nsh, 173378nsh), the Innovation Leader Project of Qingdao (168325zhc), and the First Class Discipline Project of Shandong Province.