Preparation and application of novel poly-tetrahydropyrimidine modified-mesoporous silica microspheres

Abstract

Mesoporous silica microspheres, a multifunctional material with high specific surface area, pore size, and mechanical properties, are widely used as separation and support materials. Mesoporous silica, has been relatively studied as LC column packing material for separation and detection. In this research, we prepared mesoporous silica microspheres by a simple synthesis method, and the antibacterial modification of mesoporous silica was carried out by adding synthesized PTHP. Excellent test results have been exhibited, the PTHP-SiO₂ mesoporous has the same structure and morphology as the SiO₂ microspheres, but shows excellent bacterial inactivation ability, and better separation as LC column packing material, thus can be applied as a multifunctional material.

Keywords:

• Polytetrahydropyrimidine
• antibacterial
• mesoporous silica microspheres
• separate
• liquid chromatography

Additional information

Funding

This study was supported by the National Natural Science Foundation of China (21874078, 22074072, 22274083), the Innovation and Development Joint Fund of Natural Science Foundation of Shandong Province (ZR2022LZY022), the Science and Technology Planing Project of South District of Qingdao City (2022-4-005-YY), the Exploration project of the State Key Laboratory of Bio-Fibers and Eco-Textiles of Qingdao University (TSKT202101), and the High Level Discipline Project of Shandong Province.