Phytochemical analyses and in vitro evaluation of antioxidant, antihemolytic and antibacterial activity of methanolic extract of aerial parts of marjoram (Origanum majorana L)

ABSTRACT

This work reports an in vitro study of the biological activities of the methanolic extract of the aerial parts of marjoram (Origanum majorana), including antibacterial, anti-haemolytic and antioxidant activity. The extract showed strong antibacterial activity against three bacterial strains, E. Coli, Pseudomonas aeruginosa, and Staphylococcus aureus. It also demonstrated antihaemolytic activity in human blood, inhibiting haemolysis induced by sodium chloride and temperature. The phytochemical screening revealed the presence of cathechic tannins, flavonoids, saponosids, mucilagos, and glycosids. These results suggest that the methanolic extract of marjoram could be a potential source of antimicrobial agents, and natural antioxidants.

KEYWORDS:

• Biologic activities
• Origanum majorana
• oxidative stress

Acknowledgments

The authors would like to express their sincere gratitude to Professor Moussa Houhamdi for his valuable comments and insights on the manuscript. The authors would like to thank the anonymous reviewers; and the Editor for his help. This study is supported by the Algerian Ministry of Higher Education and Scientific Research.

Disclosure statement

No potential conflict of interest was reported by the author(s).