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ABSTRACT
A distinction between vitamin B6 deficiency and inanition was shown by the determination of glutamic-oxalacetic transaminase (GOT) activity in the ovary and uterus of noninjected and gonadotrophin treated rats. While in the ovaries of vitamin B6 deficient rats the GOT activity is reduced to half of the normal, in the ovaries of starved rats the enzyme level is the same as in fed rats. Gonadotrophin administration causes a marked GOT elevation in both fed and starved rats, while in the vitamin B6 deficient rats no elevation in enzyme activity was found.
On the basis of these results it is concluded that a distinction has to be drawn between effects of inanition associated with a vitamin deficiency, and the specific vitamin effect.