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Research Article

Solving a problem about cancer treatment: how does the use of the mitotic spindle model evolve during small group discussions?

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ABSTRACT

Cell division is one of the most relevant processes in Biology, for instance, to understand the reproduction of species or the development of tumours. Learning this content requires not addressing it out of context but integrating it into real-life problems that demand students apply their knowledge about cell division. In this study, the authors examine how ten small groups of 10th grade students apply their mitosis models to solve a problem about cancer treatment; and how they progress in their application in terms of students’ discursive moves. Throughout their discussions, learners must explain what happens to a treated tumour cell which cannot finish its division. To do so, they should consider understudied ideas such as the prometaphase stage or the importance of bipolar spindle formation. Data collected are the groups' audio recordings and their written reports. The results show that all groups handle notions, such as the need for centrosomes’ duplication or microtubules-chromosomes’ attachment for mitosis to be complete, throughout the activity. Although all groups integrate two or three ideas at a time into their discourse, none of them manage to combine and contextualise all the expected ones. Implications for Biology education are discussed.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by the Autonomous University of Madrid [pre-doctoral research contract of T.E.M.], by the Ministry of Science, Innovation and Universities [PGC2018-096581-B-C22; T.E.M. & B.B.T], by the Ministry of Economy, Industry and competitiveness [EDU2017-82688-P; J.M.P.M], and by the UNESCO Chair of Education for Social Justice [T.E.M., B.B.T & J.M.P.M.]. The researchers also want to warmly thank both the students and the teachers who have assisted in the data collection;Ministerio de Ciencia, Innovación y Universidades [PGC2018-096581-B-C22];Ministerio de Economía, Industria y Competitividad, Gobierno de España [EDU2017-82688-P];;Universidad Autónoma de Madrid [Pre-doctoral research contract].

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