Walking Phase Modulates H-Reflex Amplitude in Flexor Carpi Radialis

ABSTRACT

It is well established that remote whole-limb rhythmic movement (e.g., cycling or stepping) induces suppression of the Hoffman (H-) reflex evoked in stationary limbs. However, the dependence of reflex amplitude on the phase of the movement cycle (i.e., phase-dependence) has not been consistent across this previous research. The authors investigated the phase-dependence of flexor carpi radialis (FCR) H-reflex amplitudes during active walking and in kinematically matched static postures across the gait cycle. FCR H-reflexes were elicited in the stationary forearm with electrical stimulation to the median nerve. Significant phase-dependent modulation occurred during walking when the gait cycle was examined with adequate phase resolution. The suppression was greatest during midstance and midswing, suggesting increased ascending communication during these phases. There was no phase-dependent modulation in static standing postures and no correlation between lower limb background electromyography levels and H-reflex amplitude during active walking. This evidence, along with previous research demonstrating no phase modulation during passive walking, suggests that afferent feedback associated with joint position and leg muscle activation levels are not the sole source of the phase modulation seen during active walking. Possible sources of phase modulation include combinations of afferent feedback related to active movement or central motor commands or both.

Keywords:

• central pattern generator
• interlimb
• locomotion
• reflex
• robotic exoskeleton