Abstract
The nematic lyophase of disodium cromoglycate dissolved in water can be made chiral by adding a wide variety of amino acids whose ability to induce helicity is systematically studied. Long, bulky side chains lead to small helical twisting power (HTP), whereas increased hydrophilicity of side chains leads to larger HTP. Some dipeptides have dramatically large HTP's. These factors can be understood in terms of a geometric and steric model.