Selective homonuclear Hartmann–Hahn for ¹³C→¹³C polarization transfer in solution state NMR

Abstract

Polarization transfer has become a commonplace technique for the enhancement of a variety of nuclei in high field nuclear magnetic resonance (NMR). In this paper the homonuclear Hartmann-Hahn method for polarization transfer is revisited and it is shown that a 90% transfer of polarization can be achieved experimentally between a pair of scalar coupled ¹³C nuclei in a sample of isotopically enriched glycine. This may show particular utility in the field of dynamic nuclear polarization (DNP) and could be used as an addendum to already established DNP techniques allowing the favourable enhancement to be ‘stored’ on long-lived nuclei and subsequently transferred to shorter-lived nuclei prior to observation.

Acknowledgements

This work was supported by Cancer Research UK [CUK] grant number C1060/A5117 and by Basic Technology Programme grant number GR/S23612/01.