Simple device for dissolution and sample transfer for applications in spin-hyperpolarization
 

ABSTRACT

Rapid dissolution and transfer of samples are crucial steps in hyperpolarization methods such as dissolution dynamic nuclear polarization (dDNP) and quantum-rotor-induced polarization (QRIP). Here we introduce a simple and modular dissolution transfer device, and we demonstrate its application for QRIP. This device operates with low pressures and solvent volumes compared to state-of-the-art dDNP setups. On the other hand, transfer times are longer, although sufficient for ¹³C NMR spectroscopy. Our approach does not require an additional cryostat.

GRAPHICAL ABSTRACT

KEYWORDS:

• Liquid-state NMR
• quantum-rotor-induced polarization
• Haupt effect
• dissolution DNP

Acknowledgements

The authors thank Prof. Stefan Berger, Prof. Daniel Sebastiani and Dr Matthias Findeisen for helpful discussions. C. D. would like to thank Dr Josef Heiland, the workshop and the glass workshop of the institute for the technical support in building the transfer system. Generous support of the Deutsche Forschungsgemeinschaft DFG (MA 4972/5-1) is acknowledged.

Disclosure statement

No potential conflict of interest was reported by the authors.

ORCID

Jörg Matysik http://orcid.org/0000-0002-7800-7443

Additional information

Funding

This work was supported by the Deutsche Forschungsgemeinschaft (DFG) under Grant number [MA 4972/5-1].