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Articles

The Inactivation of Pyridinethione, An Antifungal Agent, by Glucose

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Pages 636-643 | Published online: 17 Sep 2018
 

SUMMARY

By means of spectrophotometric and bioassay techniques, it has been shown that the reducing sugar D-glucose inactivates the antifungal compound sodium pyridinethione. This is dependent on time, the concentration of the reactants, and is accelerated in the presence of phosphate. The chemical interaction between glucose and pyridinethione is discussed.

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