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SUMMARY
A heterocaryon between auxotrophic strains of Cephalosporium mycophilum exhibits selective incorporation of nuclear types into the conidia when grown on minimal medium. Hyphal tips isolated from such a colony are homocaryotic and incapable of growth on minimal medium.
When the heterocaryon was grown on minimal medium supplemented with particular concentrations of nutrilites, heterocaryotic hyphal tips were isolated. It was not possible to isolate hyphal tips capable of continued propagation on minimal medium under any of the conditions investigated.
A nutritional hypothesis is proposed to explain the apparent paradox presented by the ability of heterocaryotic mycelial mat fragments to grow on minimal medium and the inability of heterocaryotic hyphal tips to grow on minimal medium.