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Original Articles

Preparation of 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, a Key Intermediate for the Synthesis of Paliperidone

, , , , &
Pages 296-302 | Received 27 May 2015, Published online: 18 May 2016
 

Acknowledgements

The authors are grateful to the management of Megafine Pharmaceuticals (P) Ltd., for supporting this work. We also thank our colleagues of the Analytical Research and Development Department, Megafine Pharmaceuticals (P) Ltd., for their valuable cooperation in developing the chromatographic methods to establish the processes and for the identification of the impurities.

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