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Pathology Volume 31, 1999 - Issue 4
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Research Article

Fatal Disseminated Infection by Scedosporium Prolificans During Induction Therapy for Acute Leukemia: A Case Report and Literature Review

David A. Westerman Peter MacCallum Cancer Institute, East Melbourne, Vic, Australia
,
Bryan R. Speed
&
H. Miles Prince
Pages 393-394 | Published online: 06 Jul 2009
 

Abstract

We report a case of fatal disseminated fungal infection by Scedosporium prolificans which occurred in a patient with acute leukemia during induction chemotherapy. Rapid clinical deterioration despite high-dose empirical amphotericin B highlights both the pathogenicity of this fungus in immunocompromised hosts and its resistance to standard antifungal therapy.

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