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Abstract
Are staphylococcal infections more frequent now than they were in the preantibiotic era? How have antibiotics influenced their occurrence? Is there evidence that strains of coagulase-positive staphylococci vary in virulence? What is “a dangerous carrier”? What is the role of the asymptomatic nasal carrier? What are the problems of eradication of the carrier state?
These questions are discussed on the basis of recent experiences in hospitals with problems in the control of resistant staphylococcal infections.