The Use of Respiratory Stimulants

Abstract

Analeptics or antinarcotics may be used to antagonize drug-induced depression of the central nervous system.

Analeptics act primarily on the medullary center and stimulate the central nervous system. They are not effective in reversing an intravenously administered anesthetic or in depressions due to physical agents or an overdosage of a volatile anesthetic or a stimulating drug.

Antinarcotics are weak narcotics rather than stimulants. They exert an antagonistic action only in the presence of an over-dosage of a narcotic; they are not effective if the depression is due to excess use of either barbiturates or other non-narcotic hypnotics.

Management of a comatose patient includes establishing an airway, administering oxygen, giving the drug indicated by the type of depression, hydrating the patient, and maintaining the correct fluid-electrolyte balance.