Abstract
Acridine-orange fluorescence microscopy for cytodiagnosis of cancer introduces new cytochemical criteria based on the increase of nucleic acids in malignant cells.
Application of this technic results in a highly polychromatic picture which conspicuously reveals the presence of suspicious or malignant cells. Morphologic diagnostic criteria are clearly presented for cytologic evaluation.
The procedure may be performed quickly and by relatively untrained personnel. The results achieved equal those obtained with conventional cytodiagnostic methods.