Classification, Diagnosis and Treatment of Hypothyroidism

Abstract

Hypothyroidism is discussed under the headings of myxedema, permanent hypothyroidism without myxedema, and cretinism. The accuracy and limitations of various laboratory tests of thyroid function are reviewed in relation to these categories. Three features which may be useful in recognition of atypical cases are abnormal menstruation, psychosis and anemia.

Treatment consists of continual replacement therapy with desiccated thyroid. In cretinism, although normal function seldom is attainable, the physician should attempt to obtain maximal benefit for the patient.