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Abstract
Diagnosis of primary hyperparathyroidism is still based on indirect procedures which detect the biochemical disturbance caused by excessive excretion of parathyroid hormone, but an encouraging start has been made toward direct measurement of hormone concentration in tissue fluid. Only a constant awareness of the varying manifestations of the disease can result in recognition of more cases during life.
Some of the aspects of primary hyperparathyroidism discussed are clinical manifestations, biochemical disturbances, radiologic and histologic features, and differential diagnosis.