Analgesic Agents for the Relief of Acute Pain

Abstract

The management of acute pain remains a challenge, and search continues for an effective analgesic without addiction liability. The authors report gratifying results achieved with the promising new analgesics alphaprodine hydrochloride, phenazocine, anileridine dihydrochloride, piminodine and an isoquinoline derivative.

Administration of tranquilizers in the overall management of pain allows use of smaller doses of narcotic analgesics. The authors have found that chlordiazepoxide effects remarkable changes in the fear factor associated with acute pain.