Present Status of Isolation Perfusion and Intra-arterial Infusion Technics

Abstract

The success of regional chemotherapy in malignancy depends chiefly on the sensitivity of the tumor to the particular agent that is used.

Isolation perfusion of chemotherapeutic agents has apparently proved effective as an adjunctive measure in certain malignancies of the extremities; in other areas, leakage of the agent into the systemic circulation is such that no value is obtained from this procedure.

Continuous intra-arterial administration of alkylating agents may prove effective in malignancies of the extremities, head and neck and pelvic regions.

All forms of isolation perfusion and intra-arterial infusion have been equally impressive in relieving pain in far-advanced malignancies.