Detection of Intracranial Lesions by Contour Brain Scanning With Radioisotopes

Abstract

Automatic contour brain scanning is compared with manual and rectilinear scanning methods. The contour scan chart corresponds closely to anatomic features, and the method allows the radiation detectors to “see” a relatively uniform volume of tissue with a more constant ratio of skull and scalp tissue to brain tissue. Foreshortening and distortion of the curved surfaces of the head are reduced to a minimum. The method is not restricted to any particular isotope. Radioactive iodinated human serum albumin is especially suitable for brain scanning because it exploits the normal selective permeability of the blood-brain barrier and also gives an indication of lesions with increased vascularity.