Nephrotic Syndrome in Children

Abstract

Mortality of children with the nephrotic syndrome has been lowered by aggressive treatment regimens designed to maintain remission from proteinuria.

Use of a large dosage of corticotropin or adrenal corticosteroids for an extended period has been successful in modifying the altered permeability of the glomerular basement membrane to plasma proteins.

In addition to employing intensive steroid therapy, symptomatic treatment and general principles of supportive care, it is most important that the physician establish an empathic relation with the family of the child with the nephrotic syndrome.