Photosensitivity Reactions in Various Diseases

Abstract

Photosensitivity is a prominent feature of various disease states. The author discusses this reaction in relation to porphyria, lupus erythematosus, pellagra, aging, carcinogenesis, xeroderma pigmentosum, solar urticaria, polymorphic light eruptions and drug-induced photosensitivity. Most cases can be managed successfully by education of the patient, protection of the skin with clothing and sunscreens, and use of appropriate systemic medications. Antimalarials are most effective in polymorphic light eruptions and discoid lupus erythematosus.