Medical Management of Cirrhosis of the Liver

Abstract

A therapeutic regimen for hepatic cirrhosis based on administration of large doses of testosterone propionate plus thiamine has led to “clinical cure” in 60 per cent of 700 cases. Clinical signs of the disease have disappeared and biochemical values have returned to normal. Therapy is continued at least three years after clinical symptoms disappear. The rationale of this method of treatment includes the theory that a deficiency of hyaluronidase activity in the liver may be responsible for the enormous growth of connective tissue.