Clinical Aspects of Enterovirus Infection

Abstract

Enteroviruses have been isolated in a wide variety of clinical syndromes. Investigations by scores of workers in many parts of the world are reviewed. Clinical manifestations of enterovirus infection include aseptic meningitis, paralytic disease, acute cerebellar ataxia, pleurodynia, neonatal infection, pericarditis and myocarditis, orchitis, enanthems and exanthems and respiratory infections. It has not yet been established that these viruses are a major cause of gastrointestinal disorders. When enterovirus infection is suspected, viral laboratory studies cannot be expected to yield meaningful results unless adequate specimens for virus isolation are submitted as well as serum collected in the acute and convalescent stages.