Low-Density Serum Lipoproteins in Survivors and Nonsurvivors of Myocardial Infarction

Abstract

Various investigations have shown that abnormal serum lipids are unquestionably associated with atherosclerotic heart disease. In a study of low-density serum lipoproteins in 151 patients with myocardial infarctions, the authors found that levels of serum cholesterol and triglycerides were significantly more abnormal in nonsurvivors than in survivors. Normal low-density serum lipoproteins were found in only 12 per cent of the survivors and 6 per cent of the nonsurvivors.

The correlation between cholesterol and triglyceride lipid fractions is extremely low and each functions independently of the other; thus, the determination of either alone is inadequate for evaluating the true extent of the lipid abnormality or therapy required.