Abstract
The phenothiazine tranquilizers are highly effective primary therapeutic agents in psychoses and are valuable adjuvants to psychotherapy in the neuroses. Endogenous depression responds readily to the antidepressant drugs of the imipramine type. In atypical depression the monoamine oxidase inhibitors play a prominent therapeutic role. Grave neuroses require the same treatment as do the psychoses. At present, outside the hospitals, one-third of all the prescriptions for psychoactive drugs specify chlordiazepoxide; meprobamate accounts for a slightly smaller proportion.