Abstract
The main medical problems associated with pituitary lesions or pituitary surgery are hypopituitarism and diabetes insipidus. Hypopituitarism is manifested by hypogonadism, hypothyroidism and, in some cases, hypoadrenocorticism. Replacement therapy is necessary to correct the hormonal deficiencies arising from dysfunction of the three target glands. Management of diabetes insipidus consists primarily of administration of antidiuretic hormone.