Hemolytic Disease of the Newborn

Abstract

Management of the erythroblastotic infant in iso-immunized pregnancies has progressed from simple exchange transfusion in 1945 through early delivery and amniotic fluid examination to the latest innovation, intraperitoneal fetal transfusion. With each improvement infant mortality has decreased, as is shown in the records of the Rh Laboratory, Winnipeg. However, continuing investigations with Rh antibody may lead to ultimate prevention of iso-immunization, with no further need for elaborate and often hazardous technics.