Abstract
Chromophobe pituitary adenomas occasionally attain sufficient size to impinge on the optic nerves or cause enlargement of the sella turcica. Headaches, visual changes, weight gain and loss of sexual drive are the chief complaints. Some disagreement exists as to whether operation should be performed immediately or an initial trial of radiation therapy tried. With high voltage x-ray treatment, however, 80 per cent of patients have improved so that no further treatment has been necessary, while 20 per cent have subsequently required operation.