Ehlers-Danlos Syndrome

Abstract

Hyperelasticity and fragility of skin and hyperextensibility of joints are the most common features of the Ehlers-Danlos syndrome, a hereditary disease resulting from a collagen disorder. The incidence of this syndrome in three generations of a kindred is reported here. Thirty-two of 58 members of the kindred were considered to be affected, including 20 males and 12 females. The literature is reviewed, and the clinical and genetic implications are discussed.