Blood Coagulation and Hemophilioid Disorders

Abstract

Hereditary bleeder states and syndromes of diffuse intravascular clotting are considered from the standpoint of laboratory diagnosis and the physiologic principles on which management is based. Availability of antihemophilic factor concentrates has revolutionized treatment of hemophilia A. The rationale for use of anticoagulants in managing diffuse intravascular clotting is outlined.