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Abstract
The most perplexing problems encountered in the medical management of heart transplant patients are recognition and management of rejection. In addition the immunosuppressive therapy given can make infection hard to recognize. In the series of 16 heart transplantations on which this report is based, eight of the 14 deaths can be attributed to rejection and four to infection. Current challenges are the clear identification of biologic mechanisms involved in rejection and the understanding of the immune mechanisms.
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Notes on contributors
Louis L. Leatherman
Dr. Leatherman was a fellow in cardiology, Baylor College of Medicine and St. Luke's Episcopal Hospital, Houston. He is now in the private practice of cardiology in Houston.
Robert D. Leachman
Dr. Leachman is director, department of cardiology, St. Luke's Episcopal Hospital. Dr. Rochelle is assistant professor of medicine. Dr. Montgomery is assistant professor of pediatrics, Dr. Harrison is associate professor of pediatrics, and Dr. Lemole is a fellow in cardiovascular surgery, Baylor College of Medicine.
Donald G. Rochelle
Dr. Leachman is director, department of cardiology, St. Luke's Episcopal Hospital. Dr. Rochelle is assistant professor of medicine. Dr. Montgomery is assistant professor of pediatrics, Dr. Harrison is associate professor of pediatrics, and Dr. Lemole is a fellow in cardiovascular surgery, Baylor College of Medicine.
John R. Montgomery
Dr. Leachman is director, department of cardiology, St. Luke's Episcopal Hospital. Dr. Rochelle is assistant professor of medicine. Dr. Montgomery is assistant professor of pediatrics, Dr. Harrison is associate professor of pediatrics, and Dr. Lemole is a fellow in cardiovascular surgery, Baylor College of Medicine.
Gunyon M. Harrison
Dr. Leachman is director, department of cardiology, St. Luke's Episcopal Hospital. Dr. Rochelle is assistant professor of medicine. Dr. Montgomery is assistant professor of pediatrics, Dr. Harrison is associate professor of pediatrics, and Dr. Lemole is a fellow in cardiovascular surgery, Baylor College of Medicine.
Gerald M. Lemole
Dr. Leachman is director, department of cardiology, St. Luke's Episcopal Hospital. Dr. Rochelle is assistant professor of medicine. Dr. Montgomery is assistant professor of pediatrics, Dr. Harrison is associate professor of pediatrics, and Dr. Lemole is a fellow in cardiovascular surgery, Baylor College of Medicine.