Twin-to-Twin Transfusion Syndrome

Abstract

Plethora in one of a pair of monozygotic twins and pallor in the other are now understood as evidence of intrauterine transfer of blood by way of vascular anastomoses in the placenta. The artery-to-vein type of communication acts as an arteriovenous shunt. The syndrome is an important cause of fetal and neonatal morbidity and mortality.