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Abstract
Serum and urinary muramidase assays are of greatest value in diagnosing myelomonocytic and chronic myelocytic leukemia and in evaluating renal tubular damage. Like all known enzymes, muramidase is a protein. The assay of this enzyme is based on its ability to hydrolyze the cell wall of Micrococcus lysodeikticus, the substrate in most turbidimetric assay methods and in the agar-plate method of Osserman.