Abstract
Treatment for acne is far from optimal. This is understandable when we consider that the pathogenesis of the disease is still controversial and there are only limited means of controlling the process at different levels. Of the therapeutic agents that are available, benzoyl peroxide and vitamin A acid used in combination have given the best results in the majority of patients. Benzoyl peroxide inhibits the formation of free fatty acids in sebum, and vitamin A acid prevents follicular hyperkeratosis.