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Benign orofacial pain stems from many causes—neuropathy, musculoskeletal disorders, even emotional stress. Because of this diversity, diagnosis is difficult, and treatment is often based on the predilection of the physician. Dr Dworkin describes the two principal types of benign chronic orofacial pain—trigeminal neuralgia and TMJ pain-dysfunction syndrome—and the various surgical and pharmacologic therapies used to relieve this often intense and intolerable pain.