The case for tight control in diabetes

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Diabetes mellitus remains one of the most formidable of diseases. Despite great advances in the past half century in the treatment of diabetic complications and their consequences, morbidity and mortality are largely unchanged. Recent evidence indicates that tight control of blood glucose levels is desirable to prevent long-term vascular consequences, although possible risks must be carefully weighed. Dr Hollander examines the issue of tight control and proposes an approach to management of diabetes based on present evidence.