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Original Articles

Nonsteroidal anti-inflammatory drugs and peptic ulcer disease

An overview

Pages 33-40 | Published online: 17 May 2016
 

Preview

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to reduce inflammation and relieve pain, particularly in patients with arthritis. However, a growing body of information indicates that NSAIDs may be a major cause of upper gastrointestinal ulcer disease. Dr Silverstein reviews the association between NSAIDs and gastroduodenal ulcers, as well as current data about prophylaxis against NSAID-induced ulceration.

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