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Original Articles

Pernicious anemia

Early identification to prevent permanent sequelae

Pages 231-237 | Published online: 17 May 2016
 

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Because pernicious anemia is easily treated, early diagnosis is essential to prevent permanent neurologic deficits. Laboratory tests include a complete blood cell count, determination of the serum cobalamin level, and the Schilling test, in which radiolabeled vitamin B12 is used to demonstrate a lack of intrinsic factor. Therapy gives rapid relief but usually must be continued for life.

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