Recognizing acetaminophen hepatotoxicity in chronic alcoholics: Postgraduate Medicine: Vol 91, No 4

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Large overdoses of acetaminophen may cause dangerous hepatotoxicity in anyone. Chronic alcoholics are a special subgroup who risk serious toxicity when taking acetaminophen in even therapeutic doses. Drs Rex and Kumar discuss the metabolism of acetaminophen and describe how it differs in chronic alcoholics and suicidal patients who overdose. In addition, the authors compare the presentation of acetaminophen hepatotoxicity with that of alcoholic hepatitis.

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Recognizing acetaminophen hepatotoxicity in chronic alcoholics

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Recognizing acetaminophen hepatotoxicity in chronic alcoholics

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