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Original Articles

Nitrate tolerance

How to prevent it or minimize its effect

, MBBS, MRCP, FRCPC
Pages 307-318 | Published online: 17 May 2016
 

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Although nitrates are powerful antianginal and anti-ischemic agents, long-term therapy may result in nitrate tolerance. How can this be avoided? Dr Thadani discusses clinically useful strategies to prevent or minimize nitrate tolerance in patients with stable angina pectoris, unstable angina, and congestive heart failure.

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