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What causes the thyroidal and ophthalmic manifestations of this autoimmune disorder? What are the advantages and disadvantages of radioactive iodine, antithyroid drugs, and surgery as means of rendering a patient euthyroid? How can the risk of treatment complications be reduced? What is the best way to manage thyroid storm? Graves' ophthalmopathy? Thyrotoxicosis in pregnancy? Drs Caruso and Mazzaferri address these and other questions.