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Just when it appeared that diuretics were becoming obsolete in the attack against hypertension, they have come charging back to the fore. This is especially true in treatment of systolic hypertension in the elderly. The perspective on diuretics and their recommendations for administration have changed recently because of the results reported from several important clinical trials. This article reviews these findings and summarizes treatment implications.
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William C. Cushman
William C. Cushman, MD Dr Cushman is chief, hypertension section, Veterans Affairs Medical Center, Memphis, and associate professor, departments of medicine and preventive medicine, University of Tennessee, Memphis, College of Medicine. He is study chairman of two national Veterans Affairs multicenter clinical trials: one on the effects of reducing alcohol Intake on blood pressure and another on the effects of various antihypertensive agents and a lipid-lowering agent on cardiovascular events in the elderly.