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As the name implies, Henoch-Schönlein purpura is a vasculitic disease, but it also affects multiple organ systems. Although the exact cause of the disease has not been determined, recent studies have shed some light on its pathogenesis. This article reviews these studies and discusses the various manifestations and possible complications. Two classification systems are also included.
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Notes on contributors
Robert Patrignelli
Robert Patrignelli, MD Dr Patrignelli (left) is a resident in dermatology, Tulane University School of Medicine, New Orleans.
Shahzad H. Sheikh
Shahzad H. Sheikh, MD Dr Sheikh (right) is chief resident, department of medicine, Bridgeport Hospital, Bridgeport, Connecticut, and clinical instructor in medicine, Yale University School of Medicine, New Haven, Connecticut.
Thomas A. Shaw-Stiffel
Thomas A. Shaw-Stiffel, MD,CM Dr Shaw-Stiffel (seated) is assistant clinical professor of medicine, University of Rochester School of Medicine and Dentistry, and director, department of internal medicine, Park Ridge Hospital, Rochester, New York.