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Macrocytosis has causes other than folate or vitamin B12 deficiency, including chronic alcohol ingestion and various forms of drug therapy. In this article, Dr Brigden presents clinical cases that illustrate five different causes of macrocytosis, with comments on each case to facilitate the overall approach to diagnosis and management.
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Notes on contributors
Malcolm L. Brigden
Malcolm L. Brigden, MD Dr Brigden is director of hematology, Island Medical Laboratories, and consultant in hematology-oncology at Victoria General and Royal Jubilee hospitals, Victoria, British Columbia.