Complications of blood transfusion

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Severe, life-threatening reactions to blood transfusion are rare but may be clinically similar to minor reactions, which are fairly common. The authors describe the manifestations of various noninfectious reactions and the laboratory workup necessary to discriminate among them. They also discuss the mechanisms of these transfusion reactions and tell how to treat and prevent them.

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Notes on contributors

Gregory D. Sloop

Dr Sloop (right) is senior resident, department of pathology, University of Alabama at Birmingham. Dr Friedberg (left) Is assistant professor; associate head, transfusion medicine; and associate medical director, blood bank, division of laboratory medicine, department of pathology, University of Alabama at Birmingham. Dr Friedberg is also chief, pathology and laboratory medicine service, Veterans Affairs Medical Center, Birmingham.

Richard C. Friedberg

Dr Sloop (right) is senior resident, department of pathology, University of Alabama at Birmingham. Dr Friedberg (left) Is assistant professor; associate head, transfusion medicine; and associate medical director, blood bank, division of laboratory medicine, department of pathology, University of Alabama at Birmingham. Dr Friedberg is also chief, pathology and laboratory medicine service, Veterans Affairs Medical Center, Birmingham.