Finally, after 56 years of type 1 diabetes: a regimen that works

ABSTRACT

Prior to the availability of degludec and regular human insulin inhalation powder in the type 1 diabetic patient glycemic control with subcutaneous insulin injections was difficult to obtain due to nocturnal, pre-prandial and often severe hypoglycemia as well as post-prandial hyperglycemia and hypoglycemia due to ‘stacking’ of insulin. A 62-year-old female with type 1 diabetes for 56 years who could not be controlled with continuous subcutaneous insulin aspart infusion obtained glycemic control without significant hypoglycemia or increased post-prandial glycemic excursions utilizing degludec insulin for basal needs and technosphere before meals and between meals if needed. The availability of degludec and technosphere insulin improved the management of brittle type 1 diabetes.

KEYWORDS:

• Diabetes mellitus type 1
• degludec insulin
• regular human insulin inhalation powder
• hypoglycemia
• post-prandial hyperglycemia

Acknowledgments

None reported.

Declaration of interest

DSHB is affiliated with Speakers Bureau Novo-Nordisk. A Postgraduate Medicine peer reviewer on this manuscript declares they are affiliated with speaker’s bureau: Mannkind, Janssen and Aegerion and consultant/advisor: BI, NovoNordisk and Bayer. All other peer reviews on this manuscript no other relevant financial or other relationships to disclose.

Additional information

Funding

This manuscript was not funded.