https://orcid.org/0000-0002-4678-4192
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ABSTRACT
Background
Hypertension is associated with stroke events. The purpose of this study was to analyze the correlation between hypertension and stroke in American adults from 2007 to 2018 in National health and Nutrition Examination Survey (NHANES) database.
Methods
28528 individuals in the NHANES from 2007 to 2018 were included in the cross-sectional analysis. The independent variable was blood pressure (BP) and the outcome variable was stroke. Multivariate linear regression model was used to study the correlation between BP and stroke.
Results
In each multivariate linear regression model, BP level was positively correlated with stroke, and this positive correlation was stable in both men and women (man OR: 1.36, 95% CI: 0.95 to 1.69; woman OR: 1.45, 95% CI: 1.12 to 1.78).
Conclusion
Our results show that there is a significant positive correlation between BP and stroke. When the systolic blood pressure (SBP) is about 140 mmHg, the risk of stroke is the lowest; Male patients with diastolic blood pressure (DBP) of about 80 mmHg have a lower risk of stroke.
KEYWORDS:
Declaration of funding
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Declaration of financial/other relationships
The authors declare no conflict of interest.
Reviewer disclosures
Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.
Author contributions
SY, SS and YJ: Conceived and designed the experiments; Performed the experiments; Analyzed and interpreted the data; Wrote the paper.
SL and DW: Contributed reagents, materials, analysis tools or data.
Data availability statement
The data that support the findings of this study are openly available in [National Health and Nutrition Examination Surveys (NHANES)] at [https://www.cdc.gov/nchs/nhanes/index.htm].