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Original Article

In vitro phagocytosis of fungal spores by rabbit lung macrophages

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Pages 152-156 | Published online: 09 Jul 2009
 

Abstract

The degree of phagocytosis by rabbit lung macrophages has been studied for the spores of 4 fungi, Aspergillus fumigatus, an aflatoxin-producing and a non-aflatoxin-producing strain of A. flavus and Rhizopus arrhizus. Parallel tests using inert particles of polystyrene of corresponding size were used. The degree of phagocytosis for all, except R. arrhizus, was markedly higher than for the corresponding particles.

Zusammenfassung

An Makrophagen von Kaninchenlunge wurde die Phagozytose der Sporen von vier Pilzen (Rhizopus arrhizus, Aspergillus fumigatus und je einem A. flavus-Stamm mit und ohne Aflatoxinbildung) gemessen. Da die Phagozytose von der Teilchengrösse beeinflusst word, erfolgten Kontrollversuche mit inerten Polystyrol-Partikeln gleicher Grösse. Mit Ausnahme derjenigen von R. arrhizus wurden die Pilzsporen bedeutend stärker phagozytiert als die gleichgrossen inerten Partikel.

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